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Wacker Biotech and Eclipsebio announce strategic collaboration to advance RNA medicine development and production
Joint press release by WACKER and Eclipsebio
Wacker Biotech, a leading contract development and manufacturing organization (CDMO) wholly owned by Wacker Chemie AG, and Eclipse Bioinnovations, Inc. (Eclipsebio), the leader in sequencing-based analytics and AI-enabled design for RNA therapeutics, today announced a strategic collaboration. The partnership will further strengthen the companies’ support of RNA therapeutic developers.
Lipids that are used to formulate mRNA active ingredients are stored in large steel tanks at WACKER’s mRNA Competence Center in Halle, Germany. Source: WACKER
This collaboration unites Eclipsebio’s integrated platform of AI-optimized RNA design and sequencing-based validation with the large-scale and GMP-compliant manufacturing of nucleic acid-based therapies at Wacker Biotech. Eclipsebio designs RNA for both manufacturability and efficacy, focusing on high yield, integrity, purity, stability, and protein expression, while WACKER’s CDMO supports the entire value chain for RNA-based therapeutic approaches, from plasmid DNA through in vitro transcription (IVT) for GMP-compliant RNA to its formulation in lipid nanoparticles (LNPs) that meet regulatory standards. Together, the companies will improve the options for drug developers to produce RNA ready for the clinic.
“We are excited to expand our collaboration with WACKER,” said Peter Chu, PhD, Co-founder and CEO at Eclipsebio. “This partnership allows us to offer innovative access and better support to our partners in every stage of the drug development pipeline, whether they need initial mRNA designs that will produce high yield or are ready for IVT scale-up.”
“We have been working together for a while now, and the new added RNA design services of Eclipsebio are an important feature for early-stage clients, which we are supporting with our newly launched contract research services (CRS),” said Hagen Richter, Head of Global Innovation BioPharma at WACKER. “This collaboration utilizes our complementary strengths to offer clients strong, clinic-ready RNA.”
Scientists at Eclipsebio's San Diego facility prepare RNA samples for sequencing-based analytics, part of the company's platform for RNA design and characterization. Source: Eclipsebio
Eclipsebio is a private biotechnology company headquartered in San Diego that combines AI-powered sequence design, rapid prototyping, and sequencing-based analytics to support RNA drug development. With extensive experience supporting early-stage basic research through preclinical therapeutic development, Eclipsebio provides unparalleled support for obtaining deep insights into RNA and therapeutic biology. The company offers its solutions as end-to-end partnerships for biopharma and project-based services for academics.
For more information about Eclipsebio, visit www.eclipsebio.com.
Wacker Biotech is a full-service contract manufacturer of recombinant proteins based on microbial systems, live microbial products (LMPs), plasmid DNA (pDNA), and ribonucleic acid (RNA) for therapeutics and vaccines. Wacker Biotech’s portfolio extends from strain/process development and analytical testing to GMP production for clinical and commercial applications. Wacker Biotech operates three GMP-compliant, FDA- and EMA-inspected production plants at its Jena and Halle sites in Germany and in Amsterdam, the Netherlands. In addition, Wacker Biotech has a GMP-compliant plant in San Diego (Wacker Biotech US Inc.) that specializes in the production of pDNA, a critical starting point for RNA therapeutics. Complementing these manufacturing sites is a central R&D Biotechnology Center in Munich, Germany offering Contract Research Services. Wacker Biotech GmbH, Wacker Biotech B.V. and Wacker Biotech US Inc. are wholly owned subsidiaries of Munich-based Wacker Chemie AG.
For more information on WACKER’s biotechnology business visit: www.wacker.com/biologics
Press Picture
WACKER mRNA competence center Halle
Lipids that are used to formulate mRNA active ingredients are stored in large steel tanks at WACKER’s mRNA Competence Center in Halle, Germany. Source: WACKER
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Eclipsebio Team
Scientists at Eclipsebio's San Diego facility prepare RNA samples for sequencing-based analytics, part of the company's platform for RNA design and characterization. Source: Eclipsebio
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