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Supporting Heart Health

Many people worry about high cholesterol levels, which are among the most important controllable risk factors for cardiovascular diseases. Dietary supplements for maintaining heart health are becoming ever more popular. And this market is predicted to show strong growth opportunities in the coming years. WACKER’s portfolio includes two different ingredients for supporting heart health: HTEssence®, a nature-identical hydroxytyrosol, and CAVAQ10®, a highly bioavailable coenzyme Q10.

Effect of LDL cholesterol on atherosclerosis

Healthy LDL cholesterol levels are a key to maintaining cardiovascular health. A clinical study has shown that HTEssence® has a beneficial effect on LDL cholesterol values. (Siefer et al., J Nutr Med Diet Care 2018, 4:025) and can thus make a positive contribution to maintaining heart health HTEssence ® is a nature-identical hydroxytyrosol of superior purity that is produced in a patented process. Available as an odorless, water-soluble powder, it can be used in functional foods and dietary supplements in the form of tablets, capsules, energy bars and functional beverages.

Change of LDL Cholesterol Values after 4 Weeks

In a clinical trial, HTEssence® achieves a change in the LDL cholesterol level of -8 % compared to the original value (-9,4 mg/dl). Twenty-nine healthy test subjects were each administered with 30 mg of hydroxytyrosol daily for four weeks.


  • The LDL cholesterol level changed significantly by -8% in a human study
  • Clinical study results, published by Siefer et al., J Nutr Med Diet Care 2018, 4:025
  • Outstanding antioxidative effect (ORAC value of 45,000 µmol TE/g)
  • Vegan
  • GRAS (no E-number)
  • High-purity product with constant technical properties

Continue reading to find out how the benefits of HTEssence® can be combined with CAVAQ10® - another WACKER product for promoting heart health.

Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble, vitamin-like substance. It is a popular antioxidant, which is held to have benefits for the cardiovascular system and to support the optimum functioning of the heart muscle. CoQ10 biosynthesis decreases with and the consequent deficits in tissue are associated with degenerative changes appearing in the course of aging. CoQ10 supplementation can improve the efficiency of energy production in human heart tissue (Rosenfeldt et al., 2003).

Since CoQ10 is a fat-soluble substance, which is poorly absorbed, many commercial products do not contain it in a readily bioavailable form. With CAVAQ10®, WACKER offers a gamma-cyclodextrin complex, whose bioavailability is 18-fold that of conventional CoQ10 products. This value was demonstrated in a human clinical study (Terao et. al., 2006) . It is a dry, free-flowing powder that is readily soluble in aqueous systems and is suitable for administration in various forms - from tablets to beverages.


  • 18-fold higher bioavailability of CoQ10
  • Comes as a dry, free-flowing powder
  • Easily dispersible in aqueous systems
  • Vegan
  • No E number, no additives

For more information about the superior bioavailability of CAVAQ10®, visit .

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