Wacker Biotech GmbH has built up a wealth of knowledge in the fermentation of microorganisms. One of our core skills is the DENSETEC^® high-cell-density fermentation of E. coli. Based on this proprietary know-how, we have developed processes with yields of up to 400 g wet biomass/liter.

Our robust fermentation processes can be validated and ensure high, reproducible yields. The The DENSETEC^® high-cell-density fermentation yields more than 10 g/l of active product.

The combination of the ESETEC^® E. coli secretion technology and the DENSETEC^® high-cell-density fermentation accelerates process development and simplifies the purification procedure, thus ensuring that your products are manufactured efficiently and cost-effectively.

Our services include:

• Development of the entire fermentation procedure from the cell bank to the commercial fermentation process
• Medium development and optimization (defined media)
• Process optimization based on the physiological needs of the microorganisms
• Process development for high-cell-density fermentation based on proprietary know-how
• Definition of key fermentation parameters
• Validation of fermentation