-
Wacker Biotech offers expertise in a wide range of modern and established analytical methods. WACKER’s central analytical laboratories provide specific know-how and service on demand.
Our analytical competence includes:
- Electrophoretic techniques: agarose gel electrophoresis, SDS PAGE, native PAGE, IEF, 2D gel electrophoresis, western blot
- HPLC techniques: RP-HPLC, IEX, SEC, affinity chromatography, peptide mapping
- Spectrophotometric tests
- Product-specific activity measurements
- N-terminal amino acid sequencing
- Mass analysis of proteins and peptides (HPLC-MS, MALDI-TOF, ESI)
- DNA detection (THRESHOLD system, PicoGreen assay)
- Quantification of host cell proteins (THRESHOLD system, generic assay)
- Endotoxin determination by LAL test
- Quantitative PCR and/or RT-PCR
- Plasmid copy number determination
- Gene expression quantification
- Stability testing of protein APIs
- Environmental monitoring (air and surfaces)
- Water analysis as per European Pharmacopoeia (e.g. TOC (total organic carbon), bioburden, endotoxin)
- Microbiological testing (e.g. microbial counts, determination of foreign microbiological contaminants, determination of antibiotic resistances, microorganism identification methods)
- Trace analysis of organic solvents by headspace GC
- Trace element analysis by AAS and ICP-OES
- Detection of antibiotic traces in protein solutions
- Antifoam agent detection by GC-MS